Which of the following is NOT listed as a key anti-inflammatory botanical for RA?

• A. Curcumin
• B. Bromelain
• C. Ginger
• D. Garlic

Answer: (D)

Anti-inflammatory effects relevant to rheumatoid arthritis come from herbs that directly modulate the inflammatory pathways involved in RA, particularly by reducing prostaglandins, cytokines, and inflammatory enzymes.

Curcumin (turmeric) is highlighted because it strongly inhibits inflammatory signaling, including NF-kB, and lowers COX-2 and cytokines like TNF-α and IL-1β. Bromelain, a pineapple enzyme, helps reduce swelling and inflammatory mediators and can support immune and inflammatory balance. Ginger contains compounds that inhibit COX-2 and 5-LOX, decreasing prostaglandin and leukotriene production.

Garlic has anti-inflammatory properties as well, but it is not listed as a key anti-inflammatory botanical for RA in NANP materials. In this context, garlic isn’t treated as one of the primary herbs specifically emphasized for RA inflammation, even though it can contribute to general anti-inflammatory effects. If you’re using garlic, note potential interactions and consult a professional as with any supplement.