Candidiasis — most important causative factor?

• A. Prolonged antibiotic use
• B. Chronic sleep deprivation
• C. Low vitamin A
• D. High fiber diet

Answer: (A)

Disruption of normal microbial balance, especially from prolonged broad-spectrum antibiotic use, is the primary driver that allows Candida to overgrow. When these antibiotics kill many of the competing bacteria that normally keep yeast in check on mucosal surfaces and in the gut, Candida can multiply more freely and cause candidiasis. Immune function can influence susceptibility, but the strongest immediate trigger among these options is antibiotic-induced dysbiosis.

Chronic sleep deprivation may weaken immune responses but isn’t the direct cause of candidiasis. Low vitamin A can affect mucosal barriers and immunity, yet it does not typically drive Candida overgrowth to the same extent. A high fiber diet generally supports gut health and microbial balance rather than promoting candidiasis.